In addition to breast cancer, what are the clinical applications of lymphoscintigraphy (sentinel lymph node mapping)?

Updated: Dec 13, 2018
  • Author: Durre Sabih, MBBS, MSc, FRCP(Edin); Chief Editor: Mahan Mathur, MD  more...
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Answer

Lymphoscintigraphy has become widely accepted in several other applications besides breast cancer, [6, 7] including malignant melanoma (stage I and II disease). [8, 4, 9] Technetium-99m tilmanocept is also used for intradermal or SC injection for melanoma mapping. [10] The Multicenter Selective Lymphadenectomy Trial concluded that sentinel node scanning is a low-morbidity procedure for evaluating the regional nodal basin in early melanoma and should become the standard of care. [11] Other applications include head and neck cancer, thyroid cancer, non–small cell lung cancer, gastric cancer, [7] penile cancer, [12] and vulvar cancers. [13]


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