What is the role of biopsy in the workup of phyllodes tumor (cystosarcoma phyllodes)?

Updated: Oct 10, 2018
  • Author: Donald R Lannin, MD; Chief Editor: John Geibel, MD, DSc, MSc, AGAF  more...
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Answer

Open excisional breast biopsy for smaller lesions and incisional biopsy for large lesions are the definitive methods for diagnosing phyllodes tumors. Fine-needle aspiration (FNA) for cytologic examination usually is inadequate for the diagnosis of phyllodes tumors. Core biopsy is more reliable, [19, 20]  but sampling errors may still occur, and it may still be difficult to distinguish the lesion from a fibroadenoma.


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