What is the role of lab tests in the workup of phyllodes tumor (cystosarcoma phyllodes)?

Updated: Oct 10, 2018
  • Author: Donald R Lannin, MD; Chief Editor: John Geibel, MD, DSc, MSc, AGAF  more...
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Answer

No specific hematologic tumor markers or other blood tests can be used to diagnose phyllodes tumors, though expression of biologic markers can discriminate between different grades of tumor. [13, 14] The immunohistochemical expression of CD10 can predict the occurrence of distant metastasis. [15] Investigation of a malignant phyllodes tumor with whole genomic and proteomic analysis revealed chromosome mutations, amplifications, and deletions. [16] Further exploration of the biology of phyllodes tumor may lead to the development of targeted treatments.


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