What are the characteristics of a malignant phyllodes tumor (cystosarcoma phyllodes)?

Updated: Jul 23, 2019
  • Author: Donald R Lannin, MD; Chief Editor: John Geibel, MD, DSc, MSc, AGAF  more...
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Answer

The characteristics of a malignant phyllodes tumor include the following [5] :

  • Recurrent malignant tumors seem to be more aggressive than the original tumor
  • The lungs are the most common metastatic site, followed by the skeleton, heart, and liver
  • Symptoms of metastatic involvement can arise from as early as a few months to as late as 12 years after the initial therapy
  • Most patients with metastases die within 3 years of the initial treatment [6]
  • No cures for systemic metastases exist
  • Roughly 30% of patients with malignant phyllodes tumors die of the disease

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