When is transfusions indicated in the treatment of lower gastrointestinal (GI) bleeding (LGIB)?

Updated: Jul 26, 2019
  • Author: Burt Cagir, MD, FACS; Chief Editor: BS Anand, MD  more...
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Answer

A hematocrit level of less than 18% or a decrease of about 6% is indicative of significant blood loss that requires blood transfusions; the goal is to achieve a target hematocrit level of approximately 20-25% in young patients and a target hematocrit level of around 30% in high-risk, older patients. A coagulopathy, such as when an international normalized ratio (INR) is greater than 1.5, may require correction with fresh frozen plasma; thrombocytopenia can be corrected with platelet transfusions.


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