What is the role of provocative bleeding studies in the diagnosis of occult lower gastrointestinal (GI) bleeding?

Updated: Jul 26, 2019
  • Author: Burt Cagir, MD, FACS; Chief Editor: BS Anand, MD  more...
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Ryan et al performed 17 elective provocative bleeding studies for occult LGIB in 16 patients. [28] Although an abnormality was identified in 50% of patients, bleeding was provoked in six (37.5%) patients. Most of the positively provoked patients (n=5) had a previously positive tagged red blood cell scintigraphy. [28] Of the six patients with provoked bleeding, three were treated with superselective embolization at the time of provoked bleeding, two were treated with estrogen therapy, and one was treated with palliative therapy. [28] Ten patients did not bleed during the provoked study. [28]

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