What rare causes of lower gastrointestinal (GI) bleeding (LGIB) should be considered in the differential diagnoses?

Updated: Jul 26, 2019
  • Author: Burt Cagir, MD, FACS; Chief Editor: BS Anand, MD  more...
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For common conditions that cause LGIB, see Etiology. Rare causes of LGIB that may need to be considered include the following:

  • Chronic radiation enteritis/proctitis
  • Ischemic colitis/mesenteric vascular insufficiency
  • Colonic/rectal varices
  • Portal colopathy
  • Solitary rectal ulcer syndrome
  • Diversion colitis
  • Vasculitides
  • Small bowel ulceration
  • GI bleeding in runners

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