What is the efficacy of early endoscopy treatment of upper gastrointestinal bleeding (UGIB)?

Updated: Sep 01, 2021
  • Author: Bennie Ray Upchurch, III, MD, FACP, AGAF, FACG, FASGE; Chief Editor: BS Anand, MD  more...
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Cooper et al studied the effectiveness of performing an early endoscopy within the first 24 hours of an acute UGIB episode and found it to be associated with reductions in the length of hospital stay, rate of recurrent bleeding, and the need for emergent surgical intervention. [103]

According to the 2010 international consensus on nonvariceal UGIB, early endoscopy (within 24 hours of presentation) is appropriate for most patients with UGIB. [104] In a retrospective review involving more than 30,000 cases, Yavorski et al showed that the mortality rates were more than twice as high in patients who did not undergo an early endoscopic procedure than for those who did undergo the procedure early on (11.1% vs 5.2%, respectively). [9] More recent data also suggest endoscopy within 24 hours may have more favorable outcomes. [57, 98]

Studies on the effectiveness of endoscopy on weekends or off-hours have inconsistently shown poorer outcomes. [105, 106]

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