What is the role of capsule endoscopy (CE) in the workup of upper gastrointestinal bleeding (UGIB)?

Updated: Sep 01, 2021
  • Author: Bennie Ray Upchurch, III, MD, FACP, AGAF, FACG, FASGE; Chief Editor: BS Anand, MD  more...
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Although not a widely available or commonly employed modality in the setting of acute UGIB, capsule endoscopy (CE) may identify low-risk lesions in UGIB, potentially allowing a subset of patients to be safely treated as outpatients. In a study of CE in patients with UGIB, of those with duodenal visualization on CE, 23 of 25 (92%) CE findings were concordant with esophagogastroduodenoscopy (EGD) for low-risk lesions that would have been candidates for outpatient management. [60] A cause for bleeding was identified in 62 (75%) patients. CE and EGD findings were concordant in 34 (55%) patients. Among the patients with positive EGD findings, 21 (38%) had negative CE results. Of these, 7 were a result of a lack of duodenal visualization. Of 28 patients with normal EGD results, 7 (25%) had positive CE results. [60]

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