How frequently is inflammatory bowel disease (IBD) comorbid with primary sclerosing cholangitis (PSC)?

Updated: Nov 21, 2019
  • Author: Vikas Khurana, MD, FACP, FACG; Chief Editor: Vinay Kumar Kapoor, MBBS, MS, FRCS, FAMS  more...
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Answer

Whereas primary sclerosing cholangitis (PSC) occurs in about 5% of patients with inflammatory bowel disease (IBD), approximately 70% of patients with PSC have IBD. [14] Of these, 87% have ulcerative colitis and 13% have Crohn colitis; however, the course of IBD is not related to PSC. Most patients are male and are diagnosed at a mean age of approximately 40 years. [25]


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