Which neoplasms cause biliary obstruction?

Updated: Oct 16, 2019
  • Author: Jennifer Lynn Bonheur, MD; Chief Editor: Vinay Kumar Kapoor, MBBS, MS, FRCS, FAMS  more...
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Neoplasms are various tumors that may lead to biliary obstruction.

  • Cholangiocarcinomas (rare tumors arising from the biliary epithelium), ampullary carcinomas (neoplasms of the ampulla of Vater), and gallbladder carcinomas (tumors with extension into the CBD) cause obstruction within the ducts.

  • Of pancreatic tumors, 60% occur in the head of the pancreas and manifest early with obstructive jaundice.

  • Metastatic tumors (usually from the gastrointestinal tract or the breast) and the secondary adenopathies in the porta hepatis that may be associated with these tumors can cause external bile duct compression.

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