What is the prevalence of relapse in patients treated with metronidazole or vancomycin for Clostridium difficile (C diff) colitis?

Updated: Jul 25, 2019
  • Author: Faten N Aberra, MD, MSCE; Chief Editor: BS Anand, MD  more...
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Relapse occurs in 20-27% of patients treated with metronidazole or vancomycin. Most recurrences occur 3 days to 3 weeks after discontinuing antibiotic treatment. Once a patient has 1 relapse, the risk for a 2nd relapse is 45%.

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