Is fidaxomicin as effective as vancomycin in the treatment of Clostridium difficile (C diff) infection (CDI)?

Updated: Jul 25, 2019
  • Author: Faten N Aberra, MD, MSCE; Chief Editor: BS Anand, MD  more...
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Answer

In several clinical trials, 200 mg of oral fidaxomicin administered every 12 hours for 10 days has been noninferior to 125 mg of oral vancomycin administered every 6 hours for 10 days for the treatment of C difficile. [57] No difference in cure rates based on C difficile disease severity was reported. Symptomatic improvement is generally expected within 2-3 days.


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