Is intestinal microbiota transplantation (IMT) effective as treatment for recurrent Clostridium difficile (C diff) colitis?

Updated: Jul 25, 2019
  • Author: Faten N Aberra, MD, MSCE; Chief Editor: BS Anand, MD  more...
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Answer

A meta-analysis of intestinal microbiota transplantation (IMT) in which intestinal microorganisms in a suspension of healthy donor stool were infused into the intestines of patients with recurrent CDI and pseudomembranous colitis found that out of 317 patients across 27 case series and reports, 92% were successfully treated with this therapy. [68] Adverse effects were uncommon. Although further study is required, this review supports use of the IMT as a promising treatment for recurrent CDI. [68]

See the Guidelines section for recent FMT guidelines recommendations.


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