Is fecal microbiota transplantation (FMT) an effective treatment of recurrent Clostridium difficile (C diff) colitis in children?

Updated: Jul 25, 2019
  • Author: Faten N Aberra, MD, MSCE; Chief Editor: BS Anand, MD  more...
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Answer

Data regarding fetal microbiota transplantation (FMT) in children with recurrent Clostridium difficile colitis are limited and focus on colonoscopic administration of FMT. Kronman et al describe 10 consecutive children who received FMT via nasogastric tube for the treatment of recurrent CDI. The children’s median age was 5.4 years, and 30% were receiving simultaneous immunosuppression. Median follow-up was 44 days, and 90% of patients resolved their CDI. The authors conclude that FMT via nasogastric tube appears to be safe, well tolerated, and effective in treating recurrent C difficile colitis in pediatric patients. [66]


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