How common is relapse of Clostridium difficile (C diff) colitis?

Updated: Jul 25, 2019
  • Author: Faten N Aberra, MD, MSCE; Chief Editor: BS Anand, MD  more...
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Relapse is generally common, occurring in up to 20-27% of cases. Relapse typically occurs 3 days to 3 weeks after the treatment is discontinued. Possible reasons for relapse include ongoing risk factors such as antibiotic exposure, failure to eradicate the organism from the colon, and reinfection from the environment.

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