Does Clostridium difficile (C diff) infection (CDI) increase the risk of colectomy in patients with IBD?

Updated: Jul 25, 2019
  • Author: Faten N Aberra, MD, MSCE; Chief Editor: BS Anand, MD  more...
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Answer

A systematic review and meta-analysis of 12 observational studies with at least moderate quality that comprised 35,057 patients with inflammatory bowel disease (IBD) with CDI and 929,259 patients without CDI found that although CDI did not appear to increase the risk of colectomy in the short term in IBD patients, over the long term, it appeared to increase the colectomy risk in those with IBD overall and in those with ulcerative colitis. [54]


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