Why is colonoscopy more useful than sigmoidoscopy in suspected Clostridium difficile (C diff) colitis?

Updated: Jul 25, 2019
  • Author: Faten N Aberra, MD, MSCE; Chief Editor: BS Anand, MD  more...
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Most patients have disease throughout the colon. However, sigmoidoscopy alone may not reveal any abnormality if the disease is confined to the right colon. Typical pseudomembranes are beyond the limit of flexible sigmoidoscopy in 10% of patients. Therefore, colonoscopy is more useful.

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