When is retesting for Clostridium difficile (C diff) infection (CDI) recommended?

Updated: Jul 25, 2019
  • Author: Faten N Aberra, MD, MSCE; Chief Editor: BS Anand, MD  more...
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C difficile testing is not recommended in asymptomatic patients due to the difficulty in distinguishing asymptomatic carriage from infection in this setting. In addition, repeat testing for C difficile is not recommended following successful treatment in a patient recently treated for CDI. [5, 43]

Retesting for C difficile is not recommended, particularly for molecular studies, as detection rates and results do not improve, and there is an associated increase in healthcare costs and the likelihood of false-positive findings. [43]

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