What are the physical findings in Clostridium difficile (C diff) colitis?

Updated: Jul 25, 2019
  • Author: Faten N Aberra, MD, MSCE; Chief Editor: BS Anand, MD  more...
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Physical examination is generally nonspecific in patients with mild C difficile infection. Fever, signs of dehydration, lower abdominal tenderness, and/or rebound tenderness (raising the possibility of colonic perforation and peritonitis) may be present.

More concerning signs include marked dehydration, marked abdominal tenderness, and distention, as well as marked rigidity and decreased bowel sounds. These may indicate the presence of complications such as toxic megacolon, and bowel perforation.

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