Which conditions should be included in the differential diagnoses of hepatic encephalopathy (HE)?

Updated: May 18, 2020
  • Author: David C Wolf, MD, FACP, FACG, AGAF, FAASLD; Chief Editor: BS Anand, MD  more...
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Differential diagnoses of encephalopathy are as follows [39] :

  • Intracranial lesions, such as subdural hematoma, intracranial bleeding, stroke, tumor, and abscess

  • Infections, such as meningitis, encephalitis, and intracranial abscess

  • Metabolic encephalopathy, such as hypoglycemia, electrolyte imbalance, anoxia, hypercarbia, and uremia

  • Hyperammonemia from other causes, such as ureterosigmoidostomy and inherited urea cycle disorders

  • Toxic encephalopathy from alcohol intake, such as acute intoxication, alcohol withdrawal, and Wernicke encephalopathy

  • Toxic encephalopathy from drugs, such as sedative hypnotics, antidepressants, antipsychotic agents, and salicylates

  • Organic brain syndrome

  • Postseizure encephalopathy

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