What is the economic burden of hepatic encephalopathy (HE)?

Updated: May 18, 2020
  • Author: David C Wolf, MD, FACP, FACG, AGAF, FAASLD; Chief Editor: BS Anand, MD  more...
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The economic burden of hepatic encephalopathy is substantial. After ascites, hepatic encephalopathy is the second most common reason for hospitalization of cirrhotic patients in the United States. [10] Hepatic encephalopathy is also the most common, possibly preventable, cause for readmission. [10] The US national expenditures related to hospitalizations for hepatic encephalopathy have been estimated to range from about $1 billion per year to upwards of $7 billion per year. [7, 11] These costs may underestimate the true economic burden of hepatic encephalopathy, in terms of the condition's negative impact on the employment and finances of patients and their caregivers. [12]

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