What is the significance of portal hemodynamics on Doppler ultrasonography in the evaluation of cirrhosis?

Updated: Jul 30, 2018
  • Author: David C Wolf, MD, FACP, FACG, AGAF, FAASLD; Chief Editor: BS Anand, MD  more...
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Answer

Kondo et al have reported that portal hemodynamics on Doppler ultrasonography may provide noninvasive prognostic implications for decompensation and long-term outcomes in patients with cirrhosis. [10] In their retrospective study of 236 cirrhotic patients (compensated, n = 110; decompensated, n = 126) (mean followup, 33.2 mo), a significant predictor for the presence of decompensation was baseline higher model for end-stage liver disease (MELD) score; moreover, signficant prognostic factors for developing cirrhosis included higher alanine transaminase levels, lower albumin levels, and lower mean velocity in the portal trunk. [10] For compensated patients, significant predictors were hepatocellular carcinoma and lower albumin levels, whereas in decompensated patients, they were elevated bilirubin levels and overt ascites. [10]


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