Which medications in the drug class Laxatives, Saline are used in the treatment of Constipation?

Updated: Jul 05, 2019
  • Author: Marc D Basson, MD, PhD, MBA, FACS; Chief Editor: BS Anand, MD  more...
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Answer

Laxatives, Saline

Saline laxatives are used for acute treatment of constipation in the absence of bowel obstruction.

Magnesium hydroxide (Phillips Milk of Magnesia, Fleet Pedia-Lax Chewable)

Magnesium hydroxide causes osmotic retention of fluid, which distends the colon and increases peristaltic activity; it also promotes emptying of the bowel.

Magnesium citrate (Citroma)

Magnesium citrate causes osmotic retention of fluid, distending the colon and increasing peristaltic activity; it promotes emptying of the bowel. The drug works within 3 hours given orally (PO) or 15 minutes given rectally (PR). It may cause electrolyte imbalance, especially in young children or patients with renal insufficiency.

Magnesium sulfate

Magnesium sulfate causes osmotic retention of fluid, which distends the colon and increases peristaltic activity; it promotes emptying of the bowel.


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