Which medications in the drug class Laxative, Stimulant; Laxative, Stool Softener are used in the treatment of Constipation?

Updated: Jul 05, 2019
  • Author: Marc D Basson, MD, PhD, MBA, FACS; Chief Editor: BS Anand, MD  more...
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Answer

Laxative, Stimulant; Laxative, Stool Softener

Emollient stool softeners cause stool to soften; stimulants increase the peristaltic activity in the gastrointestinal (GI) system.

Senna concentrate/docusate (Peri-Colace, Dok Plus, Senokot-S)

Docusate sodium allows incorporation of water and fat into stool, causing stool to soften. Sennosides induce defecation by acting directly on the intestinal mucosa or the nerve plexus, which stimulates peristaltic activity, increasing intestinal motility. The combination usually produces action 8-12 hours after administration.


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