How are lubiprostone and linaclotide used in the treatment of constipation?

Updated: Jul 04, 2019
  • Author: Marc D Basson, MD, PhD, MBA, FACS; Chief Editor: BS Anand, MD  more...
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Answer

Lubiprostone and linaclotide are FDA approved for chronic idiopathic constipation and constipation caused by irritable bowel syndrome (IBS-C). Lubiprostone is also approved for opioid-induced constipation in patients with chronic, noncancer pain. Plecanatide is only approved for chronic idiopathic constipation in adults.


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