How is treatment failure to provide adequate relief defined in chronic constipation?

Updated: Mar 30, 2020
  • Author: Marc D Basson, MD, PhD, MBA, FACS; Chief Editor: BS Anand, MD  more...
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An international expert consensus (Delphi Survey) established five symptoms and their severities to define treatment failure to provide adequate relief in patients with chronic constipation. [25] They indicated that if any one of the following five statements is applicable to a patient, their current therapy has failed to provide adequate relief. [25]

  • The patient reports an inadequate number of bowel movements most of the time in addition to having complete bowel movements occur on fewer than 3 days per week.
  • Straining is required on most occasions or is becoming worse.
  • The stool consistency has not improved on the current therapy in addition to having a Bristol Stool Scale Type 1 or Type 2 (ie, lumpy and hard or small and very hard).
  • The patient reports inadequate improvement of another symptom/sign of chronic constipation while on the current therapy
  • The current therapy is poorly tolerated, such that any relief gained is unacceptable to the patient.

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