What are pearls for the administration of an intravitreal injection for wet (exudative) age-related macular degeneration (AMD)?

Updated: Oct 10, 2019
  • Author: David T Wong, MD, FRCSC; Chief Editor: Andrew A Dahl, MD, FACS  more...
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Allow sufficient time for the anesthetic to take effect.

Aim to reduce the time between speculum insertion and injection to reduce corneal exposure time. This may reduce the amount of corneal desiccation and epitheliopathy.

Eye washout with normal saline following the procedure may reduce discomfort in patients sensitive to povidone-iodine and/or anesthetic.

Warn patients about subconjunctival hemorrhage, which can otherwise be anxiety provoking.

Reduce the risk of endophthalmitis by wearing a mask or by not speaking during the procedure.

Bilateral injections increase efficiency and convenience to the patient with no apparent risk increase. [17]

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