What are the contraindications to intravitreal injection for wet (exudative) age-related macular degeneration (AMD)?

Updated: Oct 10, 2019
  • Author: David T Wong, MD, FRCSC; Chief Editor: Andrew A Dahl, MD, FACS  more...
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Answer

Answer

Absolute contraindications to intravitreal injection are as follows:

  • Active blepharitis or external ocular surface infection is an absolute contraindication for intravitreal injections. These conditions should be treated appropriately first. [7]

Relative contraindications to intravitreal injection are as follows:

  • History of significant acute inflammation related to the agent injected. [8]
  • Recent history of adverse thromboembolic event such as stroke.

Many patients take anti-platelet or anti-coagulant agents. It is not necessary to stop these before injection.


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