Which clinical history findings are characteristic of Budd-Chiari syndrome?

Updated: Oct 10, 2018
  • Author: Praveen K Roy, MD, AGAF; Chief Editor: BS Anand, MD  more...
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Answer

The classic triad of abdominal pain, ascites, and hepatomegaly is observed in the vast majority of patients with Budd-Chiari syndrome, [18] but it is nonspecific. A high index of suspicion is needed to make the diagnosis.

If the liver has had time to develop collaterals and decompress, patients can be asymptomatic (≤20% [18] ) or present with few symptoms. As the syndrome progresses, however, it can lead to liver failure and portal hypertension with corresponding symptoms (eg, encephalopathy, hematemesis). The American Association for the Study of Liver Diseases has released guidelines for the management of acute liver failure. [19]


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