How is neurologic deterioration managed in Wilson disease?

Updated: Feb 14, 2019
  • Author: Richard K Gilroy, MBBS, FRACP; Chief Editor: Praveen K Roy, MD, AGAF  more...
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It is very important to recognize that some patients may develop worsening neurologic symptoms when therapy is initiated. In some of these instances, the chelating agent needs to be stopped and the patient should be run on zinc acetate alone. In patients on long-term treatment who show signs of progressive neurologic symptoms on chelating agents, medication compliance and dietary compliance require review, along with an assessment of the efficacy of laboratory testing.

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