What are histologic findings characteristic of neurologic Wilson disease?

Updated: Feb 14, 2019
  • Author: Richard K Gilroy, MBBS, FRACP; Chief Editor: Praveen K Roy, MD, AGAF  more...
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Answer

Observed gross anatomical changes include degeneration and cavitation, primarily involving the putamen, globus pallidus, caudate nucleus, and thalamus. Little correlation has been observed between the degree of neurologic impairment and the neuropathologic findings. The affected areas of the brain do not possess higher copper concentrations than the unaffected portions.


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