What are the physical findings of CNS involvement in Wilson disease?

Updated: Feb 14, 2019
  • Author: Richard K Gilroy, MBBS, FRACP; Chief Editor: Praveen K Roy, MD, AGAF  more...
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Answer

Central nervous system (CNS) pathology in patients with Wilson disease results from copper deposition in the basal ganglia. The resulting signs include the following:

  • Drooling

  • Dysphagia

  • Dystonia

  • Incoordination

  • Difficulty with fine motor tasks

  • Masklike facies

  • Gait disturbance


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