What is the role of repeat magnetic resonance mammography (breast MRI) exams in premenopausal women?

Updated: Feb 25, 2019
  • Author: Preeti Gupta, MD, FRCR; Chief Editor: Eugene C Lin, MD  more...
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Answer

Answer

In premenopausal patients, cyclic hormonal enhancement is a common cause of false-positive enhancement. Although efforts to image premenopausal women in midcycle usually reduce the incidence of such foci, repeat midcycle MRM can show whether an apparent lesion changes from one cycle to the next. This is characteristic of hormonally influenced, benign tissue.

If a repeat examination shows a persistent abnormality with suspicious features that cannot be localized with US, the choice is to either continue to observe the lesion or perform breast biopsy to achieve a definitive diagnosis. The decision should be based on the level of suspicion of the MRI findings in context of the breast cancer risk in that particular patient; the options should be presented to and discussed with the patient.


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