What are the indications for deep brain stimulation (DBS) surgery in patients with Parkinson disease (PD)?

Updated: Jan 24, 2019
  • Author: Robert A Hauser, MD, MBA; Chief Editor: Selim R Benbadis, MD  more...
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Answer

DBS surgery includes subthalamic nucleus (STN) stimulation, globus pallidus interna (GPi) stimulation, and thalamic deep brain stimulation (see the following images). The UK National Collaborating Centre for Chronic Conditions notes the following indications for STN and GPi in patients with Parkinson disease [23] :

  • The presence of motor complications refractory to medical therapy

  • The absence of significant comorbidities in a biologically fit individual

  • The absence of significant mental health problems (eg, depression, dementia)

  • Response to levodopa


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