Are dopamine agonists beneficial in the management of Parkinson disease (PD) patients with both motor fluctuation and peak-dose dyskinesia?

Updated: Jan 24, 2019
  • Author: Robert A Hauser, MD, MBA; Chief Editor: Selim R Benbadis, MD  more...
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Answer

Similarly, dopamine agonists can be added to levodopa to try to smooth the response. If the patient has both fluctuations and dyskinesias on levodopa, adding a dopamine agonist is likely to decrease the disease severity and could delay dyskinesias and motor fluctuations; then, an attempt can be made to lower the levodopa dose.


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