What is the goal of treating patients with Parkinson disease (PD) who experience both motor fluctuation and peak-dose dyskinesia?

Updated: Jan 24, 2019
  • Author: Robert A Hauser, MD, MBA; Chief Editor: Selim R Benbadis, MD  more...
  • Print
Answer

The treatment of patients with both motor fluctuations and troublesome peak-dose dyskinesia can be difficult. The goal of treatment in this situation is to provide as much functional time throughout the day as possible. This is accomplished by maximizing on time without troublesome dyskinesia. An attempt is made to reduce both off time and time with troublesome or disabling dyskinesia. Unfortunately, a decrease in dopaminergic therapy may increase off time, and an increase in dopaminergic therapy may worsen peak-dose dyskinesia.


Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!