Which medications are used to control symptoms of Parkinson disease (PD)?

Updated: Jan 24, 2019
  • Author: Robert A Hauser, MD, MBA; Chief Editor: Selim R Benbadis, MD  more...
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Answer

Symptomatic drug therapy

  • Usually provides good control of motor signs of Parkinson disease for 4-6 years

  • Levodopa/carbidopa: The gold standard of symptomatic treatment

  • Monoamine oxidase (MAO)–B inhibitors: Can be considered for initial treatment of early disease

  • Other dopamine agonists (eg, ropinirole, pramipexole): Monotherapy in early disease and adjunctive therapy in moderate to advanced disease

  • Anticholinergic agents (eg, trihexyphenidyl, benztropine): Second-line drugs for tremor only


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