How is anxiety treated in patients with Parkinson disease (PD)?

Updated: Jan 24, 2019
  • Author: Robert A Hauser, MD, MBA; Chief Editor: Selim R Benbadis, MD  more...
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Answer

The 2010 American Academy of Neurology (AAN) practice parameter on the treatment of nonmotor symptoms in Parkinson disease found insufficient evidence to support or refute the treatment of anxiety in Parkinson disease with levodopa. [48] However, SSRIs and venlafaxine (Effexor, Effexor XR) may be beneficial. Buspirone is well tolerated but has not been studied in this population. Benzodiazepines can be considered, but adverse effects such as cognitive impairment, somnolence, and balance problems may be concerning. Behavior modification techniques can play an important role in the treatment of anxiety. [112]


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