Which histologic findings are characteristic of shigellosis?

Updated: Aug 20, 2021
  • Author: Heba Rashid Ashraf, MD; Chief Editor: BS Anand, MD  more...
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If distinguishing between dysentery and the acute presentation of idiopathic ulcerative colitis is urgently necessary, a colonic biopsy may be useful if it is performed within 4 days of the onset of symptoms. Histologic findings of shigellosis include the following:

  • Intense neutrophilic and mononuclear cells infiltrating the lamina propria

  • Hemorrhage

  • Ulcers

  • Mucous depletion

  • Occasional crypt abscesses

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