What is the role of lab tests in the workup of shigellosis?

Updated: Aug 20, 2021
  • Author: Heba Rashid Ashraf, MD; Chief Editor: BS Anand, MD  more...
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Laboratory studies generally reveal the following findings:

  • Fecal leukocytes and erythrocytes

  • Mildly elevated hematocrit, sodium, and urea nitrogen levels are indicative of volume depletion in cases of shigellosis.

  • Leukocytosis is rare.

  • Positive findings on stool culture of a fresh fecal specimen

  • In patients who are immunocompromised (eg, infected with human immunodeficiency virus [HIV]), blood cultures are rarely helpful in cases of shigellosis.

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