What are the ACC/AHA guidelines on the primary prevention of atherosclerotic cardiovascular disease (ASCVD) for children and adolescents?

Updated: Jun 27, 2019
  • Author: Henry J Rohrs, III, MD; Chief Editor: Stuart Berger, MD  more...
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Answer

The ACC/AHA and multisociety recommendations for primary prevention of atherosclerotic cardiovascular disease (ASCVD) include the following [13] :

  • ​In children and adolescents with lipid disorders related to obesity, it is recommended to intensify lifestyle therapy, including moderate caloric restriction and regular aerobic physical activity.
  • In children and adolescents with lipid abnormalities, lifestyle counseling is beneficial for lowering low-density lipoprotein cholesterol (LDL-C).
  • In children and adolescents 10 years of age or older with an LDL-C level persistently 190 mg/dL or higher (≥4.9 mmol/L) or 160 mg/dL or higher (4.1 mmol/L) with a clinical presentation consistent with familial hypercholesterolemia (FH) and who do not respond adequately with 3 to 6 months of lifestyle therapy, it is reasonable to initiate statin therapy.

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