What are the advantages of Polysorb sutures compare to polyglactin 910 (Vicryl) sutures?

Updated: Mar 05, 2020
  • Author: Desiree Ratner, MD; Chief Editor: Dirk M Elston, MD  more...
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A study by Lin et al found the handling characteristics of Polysorb sutures to be superior to those of polyglactin 910 (Vicryl) sutures. [23] With comparable knot construction and suture sizes, the knot-breaking strength of Polysorb sutures was significantly greater than that of polyglactin 910 sutures. In addition, the mean maximum knot rundown force noted with Polysorb sutures was significantly lower than that noted with polyglactin 910 sutures, facilitating knot construction.

Drake et al used a miniature swine model to study the determinants of suture extrusion after subcuticular closure by synthetic braided absorbable sutures in dermal skin wounds. [24] Standard, full-thickness skin incisions were made on each leg and abdomen. The wounds were closed with either Polysorb or polyglactin 910 sutures.

Each of the skin incisions was closed with five interrupted subcuticular vertical, loops secured with a surgeon’s knot. [24] The loops were secured with three-throw knots in one pig, four-throw knots in the second pig, and five-throw knots in the third pig. Suture extrusion, wound dehiscence, stitch abscess, and granuloma formation were all observed.

The cumulative incidence of suture extrusion over 5 weeks ranged from 10% to 33%. Polyglactin 910 sutures had a higher cumulative incidence of suture extrusion than Polysorb sutures did (31% vs 19%). [24] With Polysorb sutures, the five-throw surgeon’s knot had a higher cumulative incidence of suture extrusion than the three-throw or four-throw surgeon’s knot (30% vs 17% and 10%, respectively).

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