What are the abdominal symptoms of Peutz-Jeghers syndrome (PJS)?

Updated: Oct 11, 2018
  • Author: Buu Anh T To, MD; Chief Editor: Praveen K Roy, MD, AGAF  more...
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The most frequent symptom is recurrent colicky abdominal pain caused by obstruction and transient intussusceptions. [78] Melena and rectal bleeding occur less frequently, and hematemesis is uncommon. [79] Certain reports suggest that nearly 50% of the patients experience an intussusception during their lifetime, most often in the small intestine. [21]

Protein-losing enteropathy should be considered as a possible clinical manifestation or presentation of significant gastrointestinal, especially colorectal, polyp burden.

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