What prophylactic regimen is effective in reducing the risk of NSAID-related ulcers?

Updated: Apr 26, 2021
  • Author: BS Anand, MD; Chief Editor: Philip O Katz, MD, FACP, FACG  more...
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Prophylactic regimens that have been shown to dramatically reduce the risk of NSAID-induced gastric and duodenal ulcers include the use of a prostaglandin analog or a PPI according to the following regimens:

  • Misoprostol 100-200 mcg PO 4 times per day

  • Omeprazole 20-40 mg PO every day

  • Lansoprazole 15-30 mg PO every day

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