How are NSAID-related ulcers prevented?

Updated: Apr 26, 2021
  • Author: BS Anand, MD; Chief Editor: Philip O Katz, MD, FACP, FACG  more...
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Answer

Primary prevention of NSAID-induced ulcers includes the following:

  • Avoid unnecessary use of NSAIDs

  • Use acetaminophen or nonacetylated salicylates when possible

  • Use the lowest effective dose of an NSAID and switch to less toxic NSAIDs, such as the newer NSAIDs or COX-2 inhibitors, in high-risk patients without cardiovascular disease


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