What testing should be performed in the emergency department (ED) for suspected peptic ulcer disease (PUD)?

Updated: Apr 26, 2021
  • Author: BS Anand, MD; Chief Editor: Philip O Katz, MD, FACP, FACG  more...
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The emergency department (ED) workup will vary depending on presentation and includes the following:

  • Complete blood cell (CBC) count is used to evaluate acute or chronic blood loss.

  • Electrolytes, blood urea nitrogen (BUN), and creatinine levels are useful tests for critical-appearing patients who require fluid resuscitation.

  • Type and screen and crossmatched blood for transfusion is indicated in unstable or potentially critical patients.

  • Activated partial thromboplastin time (aPTT), prothrombin time (PT) and international normalized ratio (INR) are indicated in patients with active bleeding and those on anticoagulants.

  • Amylase, lipase, and liver transaminase levels can be helpful to rule out other common causes of epigastric pain.

  • Patients younger than 55 years with no alarm features should be referred for noninvasive testing for H pylori infection in the outpatient setting. [1]

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