What is the prevalence of peptic ulcer disease (PUD) in the US?

Updated: Mar 25, 2020
  • Author: BS Anand, MD; Chief Editor: Philip O Katz, MD, FACP, FACG  more...
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Answer

In the United States, peptic ulcer disease affects approximately 4.6 million people annually, with an estimated 10% of the US population having evidence of a duodenal ulcer at some time. [20]  H pylori infection accounts for 90% of duodenal ulcers and 70-90% of gastric ulcers. [21] The proportion of people with H pylori infection and peptic ulcer disease steadily increases with age.

The prevalence of peptic ulcer disease has shifted from predominance in males to similar occurrences in males and females. The lifetime prevalence is approximately 11-14% in men and 8-11% in women. [20] Age trends for ulcer occurrence reveal declining rates in younger men, particularly for duodenal ulcer, and increasing rates in older women.


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