What are less common complications of chronic pancreatitis?

Updated: Jul 15, 2019
  • Author: Jason L Huffman, MD; Chief Editor: BS Anand, MD  more...
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Diabetes mellitus is a late manifestation in about one third of patients. The tendency to develop ketoacidosis is low.

The presence of the splenic vein at the posterior surface of the pancreas predisposes it to thrombosis from adjacent pancreatic inflammation. Patients who are affected can develop gastric varices as a result of associated portal hypertension. Splenectomy is usually curative for patients who develop bleeding from gastric varices.

Pseudoaneurysm is rare, but it can be a deadly complication. Affected vessels, including the splenic, hepatic, gastroduodenal, and pancreaticoduodenal arteries, are in close proximity to the pancreas. Surgery for bleeding pseudoaneurysms is challenging and is associated with high morbidity and mortality.

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