Which vaccination should be given for the prevention of H1N1 influenza (swine flu) in the elderly?

Updated: Apr 09, 2019
  • Author: Michael Stuart Bronze, MD; Chief Editor: Russell W Steele, MD  more...
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Answer

Vaccination may provide less protection against influenza in patients older than 65 years. In an effort to improve the immunogenicity of influenza virus vaccine in elderly adults, a high-dose trivalent inactivated influenza vaccine (Fluzone High-Dose) was been developed. In a multicenter, randomized, double-blind controlled trial involving elderly adults (≥65 years), those who received the high-dose vaccine exhibited a statistically significantly higher seroconversion rate than those who received the standard-dose vaccine. [39]


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